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KMID : 0043320110340071077
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Archives of Pharmacal Research
2011 Volume.34 No. 7 p.1077 ~ p.1084
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Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents
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Rohini Rondla
Reddy P. Muralidhar
Shanker Kanne
Kanthaiah Kodipelli
Ravinder Vadde
Hu Anren
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Abstract
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A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones R-CO-Rl /R-CO-X-CO-Rl (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, 1H-NMR, 13C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.
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KEYWORD
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Azomethines, Synthesis, Antibacterial activity, Antifungal activity
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